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Table 2 Performance of the three prediction protocols

From: Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles

Subfamily

HMMER (Sn/Sp)

PSSM-15 (Sn/Sp)

PSSM-44 (Sn/Sp)

AcCS

0.96/1

0.95/1

0.96/1

4CL

0.98/1

0.92/1

0.92/1

LCS

0.98/0.96

0.93/0.96

0.98/0.95

Luciferase

1/1

1/0.99

1/1

MCS

0.91/0.99

0.83/0.97

0.91/0.99

NRPS

0.95/1

0.95/0.98

0.94/0.99

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BMC Bioinformatics

ISSN: 1471-2105

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