Figure 3

Composition. Comparison of the mean amino acid compositional changes calculated on the basis of 65 orthologous membrane proteins [4] observed in the direction from the mesophile to the psychrophile group. Error bars represent the empirical standard deviations. By the cumulative Mann-Kendall trend test the amino acids A, R, N, Q, I, K, T and V have a significant change (p-values < 0.05).