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Figure 2 | BMC Bioinformatics

Figure 2

From: Validation and characterization of DNA microarray gene expression data distribution and associated moments

Figure 2

Scatter of mean log ratio versus coefficient of variation, skewness and kurtosis of distribution of gene expressions for the two Rosetta/Merck data sets. The green curves in each of the plots represent the loess curves for scatter of each of the three higher moments (coefficient of variation, skewness and kurtosis) versus the mean log ratio of the gene expression for all those genes whose absolute value is less than 0.05. The red curves represent the best fit polynomials for scatter of the higher moments versus the mean for all those genes or probe sets whose absolute value of the mean log ratio of gene expression is greater than 0.05. The fitted trend is linear between the logarithm of the coefficient of variation and the mean of the distribution of the log of gene expression ratio and constant for the relationships between skewness and mean and between kurtosis and mean.

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