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Table 5 Coefficients of the quadratic trends between the kurtosis and skewness of the distribution of the logarithm of gene expression for each of the three data sets.

From: Validation and characterization of DNA microarray gene expression data distribution and associated moments

Data set Constant Linear Quadratic R2 p-value
Craniofacial 2.96 ± 0.04 -0.31 ± 0.07 1.40 ± 0.03 0.91 0
Liver 3.30 ± 0.07 0.12 ± 0.10 1.42 ± 0.06 0.58 0
Brain 2.97 ± 0.03 0.03 ± 0.03 1.31 ± 0.03 0.65 0
Male 3.65 ± 0.34 -0.05 ± 0.27 1.21 ± 0.07 0.82 0
Female 3.85 ± 0.27 -0.12 ± 0.20 1.23 ± 0.05 0.89 0
  1. Also included in the table are the 95% confidence intervals for these coefficients, the coefficient of determination, R2 and the p-value for the goodness of fit F-test to the linear model. Note that the models are computed using data over those probe sets with mean expression greater than 6 in order to avoid analysis with noisy or low expression genes.