Skip to main content

Table 1 Main biological processes in response to IL-6

From: Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation

Source Mode Biological process
1 positive (external) stimulus, inflammatory response
  negative (fructose) metabolic process
2 positive early cell cycle and division
  negative metabolic process, apoptosis
3 positive late cell cycle and division
  negative -
4 positive translation, coagulation
  negative (protein) metabolic process
  1. Summary of the main biological processes in hepatocytes regulated as response to IL-6. Mode indicates genes with significant positive (≥2) or negative (≤-2) contribution to the source. The main biological processes found for the corresponding group of genes are given in the last column.