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Table 2 Enzyme classes with extreme clustering properties

From: BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation

EC No.

Trees

Sequences

Seqs/Trees

3.1.21.4

73

94

1,29

3.1.6.1

5

11

2,20

1.2.7.7

6

15

2,50

3.2.1.37

6

15

2,50

5.4.99.5

7

18

2,57

1.1.99.-

5

13

2,60

2.1.1.113

8

21

2,63

3.2.1.73

5

14

2,80

3.2.1.55

9

26

2,89

1.6.99.-

5

15

3,00

2.4.1.198

8

24

3,00

3.4.16.4

6

18

3,00

4.2.1.75

5

15

3,00

4.2.2.10

4

12

3,00

EC No.

Trees

Sequences

Seqs/Trees

2.8.1.8

1

389

389,00

2.1.2.3

1

392

392,00

1.1.1.267

1

393

393,00

4.1.1.37

1

426

426,00

6.1.1.10

1

436

436,00

2.2.1.7

1

440

440,00

2.6.1.9

1

446

446,00

2.5.1.7

1

458

458,00

2.1.2.11

1

468

468,00

4.2.1.19

1

472

472,00

4.2.1.9

1

496

496,00

  1. Table 2 displays 20 enzyme classes with extreme clustering properties. Sequences within the upper ten enzyme classes have low sequence similarity and therefore cluster in multiple trees, whereas the sequences in the lower ten enzyme classes are so similar that they cluster in only one tree.