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Table 4 Filters used in the candidate scoring process

From: A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins

Site score

Description

Cons 80

The predicted stem has a conservation score of ≥ 80

Cons 90

The predicted stem has a conservation score of ≥ 90

AG mutation

If a distant sub-tree has a DNA coded G at the position of an A-G mismatch (see also Figure 5).

AG_both

There are A-G mismatches on both stem arms

Annotated aa change

The A-G mismatch results in an amino-acid discrepancy

ds G

The nucleotide downstream of the A-G mismatch position is a G