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Table 6 Verified novel sites of editing

From: A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins

Gene

Coverage

#G

#A

Freq. of G

aa change

Gabra3

679

631

48

92.93%

I/M

Elavl2

633

9

624

1.422%

I/V

Elavl2

625

15

610

2.400%

N/D

Elavl4

443

4

439

0.903%

3' UTR

Elavl4

462

3

459

0.649%

3' UTR

Elavl4

220

2

218

0.909%

T/A

Matr3

220

3

217

1.364%

R/G

Stk22c

209

2

207

0.957%

D/G

Ube1x

349

3

346

0.860%

I/M

Xpo7

390

3

387

0.769%

D/G

Hnrph2

265

2

263

0.755%

K/E

  1. Top edited genes with sites having editing p-value < 0.0001 (combined phred score for the probability of erroneous sequencing). Coverage indicates the total number of sequences, #G is edited sequences and #A the number of non-edited sequences, giving the frequency of editing (Freq. of G) and the implied amino acid change (aa change).
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BMC Bioinformatics

ISSN: 1471-2105

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