TY - JOUR AU - Jeffries, Clark D. AU - Perkins, Diana O. AU - Guan, Xiaojun PY - 2010 DA - 2010/12/20 TI - Gene processing control loops suggested by sequencing, splicing, and RNA folding JO - BMC Bioinformatics SP - 602 VL - 11 IS - 1 AB - Small RNAs are known to regulate diverse gene expression processes including translation, transcription, and splicing. Among small RNAs, the microRNAs (miRNAs) of 17 to 27 nucleotides (nts) undergo biogeneses including primary transcription, RNA excision and folding, nuclear export, cytoplasmic processing, and then bioactivity as regulatory agents. We propose that analogous hairpins from RNA molecules that function as part of the spliceosome might also be the source of small, regulatory RNAs (somewhat smaller than miRNAs). SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-11-602 DO - 10.1186/1471-2105-11-602 ID - Jeffries2010 ER -