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Table 2 Influence of the CCSB-YI1 FDR on the LowBP-LC well-studied false negative rate.

From: New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size

CCSB-YI1 FDR

Uetz-Screen

Ito-Core

CCSB-YI1

Y2H-Union

Tarassov

HT-Union

0.15

0.67

0.66

0.65

0.68

0.57

0.66

0.25

0.63

0.62

0.61

0.64

0.53

0.62

0.35

0.59

0.57

0.57

0.58

0.48

0.56

  1. The false negative rate of LowBP-LC restricted to interactions involving well-studied proteins is computed with the different datasets, when the CCSB-YI1 FDR ranges from 0.15 to 0.35, using a well-studied cutoff set at 125.
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BMC Bioinformatics

ISSN: 1471-2105

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