Figure 2From: ICC-CLASS: isotopically-coded cleavable crosslinking analysis software suiteScheme of cleavage of inter-peptide (top), dead-end (middle), and intra-peptide (bottom) crosslinks. An example with eight deuterium atoms as isotopic labels is shown. Dead-end and intra-peptide crosslinks can be identified based on specific mass losses (Mclohloss and Mcliloss, respectively), due to cleavage of the crosslinker.Back to article page