Figure 6
From: Haplotype allelic classes for detecting ongoing positive selection
Using the Svd test at the MCM6 locus. Plot of the negative log p-values for the 26 SNPs in the MCM6 locus in CEU. The reference major allele frequency haplotype is shown on top. Stars indicate derived alleles and the red star corresponds to the T-13910 mutation (rs4988235), believed to be responsible for the trait in Europeans [28]. P-values were obtained as described in Methods and the dotted and dashed line delimit p = 0.1 and p = 0.05 cutoff, respectively.