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Table 2 Results of Svd scan in ten chromosome 2 genes under positive selection according to previous reports

From: Haplotype allelic classes for detecting ongoing positive selection

  

CEU

ASI

YRI

Genes (chr2)

Ref studies

Most significant SNP

p value( S )

iHS p value

Most significant SNP

p value( S )

iHS p value

Most significant SNP

p value( S )

iHS p value

ALMS1

[25]

-

-

-

rs11126402

5.13·10-4

(400)

0.755

-

-

-

EDAR

[2527]

-

-

-

rs17036146

1.45·10-5

(800)

1.05·10 -3

-

-

-

DIRC1

[26]

-

-

-

rs7578063

9.68·10-6

(400)

0.608

-

-

-

GTF3C3

[25]

rs10163352

1.85·10-3

(400)

6.15·10 -3

rs12989157

1.88·10-4

(200)

9.74·10 -3

-

-

-

MCM6

[2]

rs4988235

7.88·10-4

(800)

3.61·10 -4

-

-

-

-

-

-

LRP1B*

[26]

-

-

-

-

-

-

rs10194564

1.67·10-4

(600)

0.209

MGAT5

[25]

rs1561277

3.15·10-5

(200)

6.72·10-2

rs7608637

1.46·10-3

(200)

0.753

-

-

-

SLC3A1

[27]

-

-

-

-

-

-

rs1067321

5.55·10-5

(600)

0.149

ADCY3

[2]

-

-

-

-

-

-

rs713587

1.11·10-4

(800)

5.98·10 -3

SUCLG1*

[25]

rs10210248

3.60·10-5

(400)

0.787

rs6721249

6.44·10-4

(800)

3.82·10-2

-

-

-

  1. Table reports rs ID of SNPs showing the most significant signal as indicated by its p-value at window size indicated in parenthesis (* the signal appears in the upstream region of the gene). For each significant signal, the p-value computed for iHS in the gene and population by the Haplotter web tool is reported (significant values at p < 0.01 are written in bold).