Table 3 Decision tree weights
From: Using simple artificial intelligence methods for predicting amyloidogenesis in antibodies
Edge | Weight | Reference for weight |
|---|---|---|
CDR | 1.0 | Ratio of CDR:FR mutations |
FR | 0.79 | |
CDR - exposed | 0.78 | Ratio of buried:exposed CDR mutations |
CDR - buried | 1.0 | |
FR - exposed | 1.0 | Ratio of buried:exposed FR mutations |
FR - buried | 0.85 | |
CDR - exposed - Δ | 0.69 | Ratio of mutations increasing (Δ) sheet-forming propensities to mutations decreasing (▽) sheet-forming propensities in exposed CDR residues |
CDR - exposed - â–½ | 0.31 | |
CDR - buried - Δ | 1.00 | Ratio of mutations increasing (Δ) sheet-forming propensities to mutations decreasing (▽) sheet-forming propensities in buried CDR residues |
CDR - buried - â–½ | 0.76 | |
FR - exposed - Δ | 1.00 | Ratio of mutations increasing (Δ) sheet-forming propensities to mutations decreasing (▽) sheet-forming propensities in exposed FR residues |
FR - exposed - â–½ | 0.95 | |
FR - buried - Δ | 0.74 | Ratio of mutations increasing (Δ) sheet-forming propensities to mutations decreasing (▽) sheet-forming propensities in buried FR residues |
FR - buried --â–½ | 0.43 |