Figure 3From: An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq dataWorkflow of the SIPeS algorithm. Using mapped paired-end reads information to compute the fragment pileup value for each point in chromosome i, then a signal map is constructed starting from baseline 1 until t (t = the maximum baseline to construct the signal map). Each signal map satisfies the user-set thresholds with a single global summit called as a candidate binding site when the baseline is smaller than t.Back to article page