Figure 2

Fraction of True Positives for different E-value bins for different subsets of BLAST hits with that E-value. The fraction of True Positives for all BLAST hits ('BLAST', blue line), the BLAST hits for which both the human query as the yeast hit are part of a co-complex network ('BLAST+cocomplex', red line), the BLAST hits for which both the human query as the yeast hit are part of a co-complex network and both have a direct co-complex network neighbour that has a clear ortholog in the other species (is part of a human-yeast Inparanoid cluster) ('BLAST+cocomplex+inparanoid', brown line), the BLAST hits for which both the human query as the yeast hit are part of a co-complex network and both have a direct co-complex network neighbour and these neighbours are clear orthologs of each other (are part of the same human-yeast Inparanoid cluster) ('BLAST+network alignment', green line).