Figure 6

Examples of COMA performing better than DALI, a structure-based method. (A) COMA and DALI, each aligns d1ks9a2 with d1uwva2, but with different domains, catalytic and central, respectively. Coloring of d1ks9a2 and the catalytic domain of d1uwva2 corresponds to the progression of polypeptide chain from N-(blue) to C-terminus (red). (B) Homologous pair of EF-hand proteins, human psoriasin (d1psra_) and pike parvalbumin (d2pvba_).