| |
Allele Name
|
Binders
|
Non-Binders
|
Total
|
DynaPredPOS
|
NetMHC
|
SVMHC
|
YKW
|
|---|
| | |
(n)
|
(n)
|
(n)
|
AUC
|
AUC
|
AUC
|
AUC
|
|
1
|
A*0101
|
163
|
1316
|
1479
|
0.93
|
0.98
|
0.95
|
0.94
|
|
2
|
A*0201
|
1544
|
1929
|
3473
|
0.93
|
0.96
|
0.92
|
0.91
|
|
3
|
A*0202
|
723
|
697
|
1420
|
0.88
|
0.93
|
0.85
|
0.85
|
|
4
|
A*0203
|
732
|
685
|
1417
|
0.88
|
0.95
|
0.86
|
0.84
|
|
5
|
A*0206
|
633
|
782
|
1415
|
0.88
|
0.95
|
0.87
|
0.86
|
|
6
|
A*0301
|
637
|
1618
|
2255
|
0.89
|
0.96
|
0.88
|
0.80
|
|
7
|
A*1101
|
816
|
1279
|
2095
|
0.92
|
0.96
|
0.90
|
0.91
|
|
8
|
A*2402
|
202
|
464
|
666
|
0.80
|
0.85
|
0.78
|
0.81
|
|
9
|
A*2601
|
69
|
885
|
954
|
0.84
|
0.93
|
0.83
|
0.84
|
|
10
|
A*3101
|
510
|
1480
|
1990
|
0.89
|
0.95
|
0.89
|
0.88
|
|
11
|
A*3301
|
203
|
994
|
1197
|
0.88
|
0.96
|
0.89
|
0.88
|
|
12
|
A*6801
|
578
|
620
|
1198
|
0.85
|
0.92
|
0.82
|
0.81
|
|
13
|
A*6802
|
439
|
980
|
1419
|
0.84
|
0.93
|
0.85
|
0.83
|
|
14
|
B*0702
|
238
|
1110
|
1348
|
0.94
|
0.98
|
0.94
|
0.93
|
|
15
|
B*0801
|
23
|
687
|
710
|
0.82
|
0.99
|
0.78
|
0.79
|
|
16
|
B*1501
|
182
|
836
|
1018
|
0.86
|
0.97
|
0.89
|
0.90
|
|
17
|
B*2705
|
81
|
917
|
998
|
0.93
|
0.97
|
0.90
|
0.94
|
|
18
|
B*3501
|
273
|
578
|
851
|
0.83
|
0.93
|
0.84
|
0.85
|
|
19
|
B*4001
|
94
|
1112
|
1206
|
0.90
|
0.97
|
0.93
|
0.91
|
|
20
|
B*4402
|
76
|
136
|
212
|
0.77
|
0.84
|
0.75
|
0.76
|
|
21
|
B*4403
|
71
|
142
|
213
|
0.68
|
0.81
|
0.65
|
0.70
|
|
22
|
B*5101
|
108
|
249
|
357
|
0.82
|
0.93
|
0.80
|
0.81
|
|
23
|
B*5301
|
127
|
228
|
355
|
0.86
|
0.95
|
0.85
|
0.87
|
|
24
|
B*5801
|
78
|
893
|
971
|
0.90
|
0.99
|
0.93
|
0.93
|
| |
Average AUC
| | | |
0.86
|
0.94
|
0.86
|
0.86
|
- Alleles included in the study with the number of binders and non-binders available; all available binders and non-binders were included in the analysis irrespective of whether quantitative laboratory test data was available or not (Dataset F). Only unique peptide sequences were included in the counts; all peptides with more than one entry for a particular allele in IEDB were counted once only. The overall performance of the four prediction models on different alleles is shown; AUC = area under the curve (ROC analysis). The average AUC for each method is included at the bottom of each column.
