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Figure 4 | BMC Bioinformatics

Figure 4

From: Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments

Figure 4

Comparison of biological, library preparation, and flow-cell effects. Boxplots of estimated log-fold-changes for UHR vs. Brain biological effects (GLM 2 in [Additional file 2: Supplemental Table S4]), flow-cell effects adjusting for biology (GLM 4), library preparation effects within flow-cell (GLM 7). Estimates are presented for total-count (black) and upper-quartile (blue) normalization.

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