BMC Bioinformatics

Table 1 Definition of true and false positive rates. Synopsis of the rules for calling true/false positives and negatives, which take into account the sign of the direction of differential expression: "+" for over-expression in UHR, "-" for over-expression in Brain.

From: Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments

		mRNA-Seq
		Non-DE	DE +	DE-
	Non-DE	TN	FP	FP	N
qRT-PCR	DE +	FN	TP	FP	P
	DE-	FN	FP	TP

The true positive rate (TPR) is estimated as TP/P and the false positive rate (FPR) as FP/N.

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ISSN: 1471-2105

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