Table 2 Empirically estimated performance measures for the tests of differential connectivity of single genes using correlation scores applied at a targeted nominal level of 5%.
From: A statistical framework for differential network analysis from microarray data
n | ρ | Sensitivity | Specificity | TDR | TNR | ||||
|---|---|---|---|---|---|---|---|---|---|
unadjusted | adjusted | unadjusted | adjusted | unadjusted | adjusted | unadjusted | adjusted | ||
50 | .5 | .990 | .893 | .949 | .970 | .951 | .970 | .989 | .982 |
200 | 1 | 1 | .946 | .970 | .949 | .971 | 1 | 1 | |
50 | .7 | 1 | 1 | .948 | .969 | .951 | .970 | 1 | 1 |
200 | 1 | 1 | .950 | .973 | .952 | .973 | 1 | 1 | |
50 | .9 | 1 | 1 | .946 | .969 | .948 | .970 | 1 | 1 |
200 | 1 | 1 | .948 | .968 | .950 | .969 | 1 | 1 | |