Table 3 Empirically estimated performance measures for the tests of differential connectivity of single genes using correlation scores applied at a targeted nominal level of 5%.
From: A statistical framework for differential network analysis from microarray data
n | ρ | Sensitivity | Specificity | TDR | TNR | ||||
|---|---|---|---|---|---|---|---|---|---|
unadjusted | adjusted | unadjusted | adjusted | unadjusted | adjusted | unadjusted | adjusted | ||
50 | .5 | .760 | .340 | .947 | .996 | .616 | .913 | .973 | .931 |
200 | 1 | .999 | .949 | .994 | .687 | .946 | 1 | 1 | |
50 | .7 | .986 | .862 | .948 | .993 | .676 | .935 | .998 | .985 |
200 | 1 | 1 | .949 | .993 | .685 | .943 | 1 | 1 | |
50 | .9 | 1 | .996 | .946 | .992 | .675 | .936 | 1 | 1 |
200 | 1 | 1 | .949 | .994 | .684 | .948 | 1 | 1 | |