Figure 2

Projection of the data into the conformational space of the internal angles ( ϕ ₁ , ϕ ₂ , θ ). Each dot (orange) corresponds to a fragment. The plot is split at the periodic boundary -180/180° of the θ angle, while the angle range of the θ₁ and θ₂ dimensions has been cropped to the populated region. Fragments of the M32K25 alphabet (see text) are shown as labelled circles and four selected fragments (Y blue, U red, P cyan, A yellow) are rendered as ball-and-stick models on the right panel. The left models illustrate the [ϕ₁, ϕ₂] angles and the right models the θ angle. The relation between the two views is a 90° rotation around a vertical axis in the paper plane and an adjustment to align the two central atoms to a Newman projection. Atom '1' is positioned left (left models) and front (right models). The plot was produced with the R package scatterplot3d [63] and the side panel with PyMol [64].