A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles

Table 2 The number of protein complexes, the total protein counts in complexes, and unique proteins in complexes in the gold-standard protein complex data and predicted protein complexes.

	*Number of Complex*	*Number of Protein*	*Number of Unique Protein*
*Protein Complexes*
Aloy *et al.*	78	626	588
MIPS	199	3165	1200
*Predicted Protein Complexes*
CEZANNE	14	471	471
HUNTER	52	908	842
CMC(size > 2)	530	4145	1826
Core(size > 2)	434	2826	1964

The input datasets of this experiment are derived from Aloy et al. and MIPS, and are available in supplementary S10 and S11. Protein complex lists defined in these two datasets are used as gold-standard lists. The predictions based on the test interactome (supplementary S2) and the expression profile (supplementary S3) are available in supplementary S13 for the two dataset respectively.

ISSN: 1471-2105