Predicting the protein-protein interactions using primary structures with predicted protein surface

BMC Bioinformatics

Table 4 Overlap between predicted and structural surface.

	*Acc*. (%)	Fm. (%)	*Prec*. (%)	*Sens*. (%)	*Spec*. (%)
Trial 1	76.1	81.3	76.0	87.3	59.7
Trial 2	76.3	81.2	71.1	94.5	54.9
Trial 3	78.6	82.3	74.2	92.5	62.3
Trial 4	77.2	81.3	83.3	79.4	73.7
Trial 5	95.1	96.2	92.7	100.0	86.9
Trial 6	88.0	90.2	82.2	100.0	73.3
Trial 7	95.1	96.2	92.7	100.0	86.9
Trial 8	95.1	96.2	92.7	100.0	86.9
Trial 9	83.0	83.1	92.4	75.4	92.4
Trial 10	93.4	94.7	100.0	90.0	100.0
Overall	85.8 ± 8.4	88.3 ± 7.0	85.7 ± 9.7	91.9 ± 9.0	77.7 ± 15.2

The equation of each measurement is identical to Table 2, while the definitions of the abbreviations used are different: TP is the number of residues within the structural surface and are correctly included in the predicted surface; FN is the number of residues within the structural surface but are incorrectly excluded from the predicted surface; TN is the number of residues outside the structural surface and are correctly excluded from the predicted surface; and FN is the number of residues outside the structural surface but are incorrectly included in the predicted surface.

ISSN: 1471-2105