Table 3 Power of F_HapMiner and the single-locus TDT (SL-TDT) using the GAW dataset on the rare haplotype model (sample size = 200 pedigrees).
From: A novel approach for haplotype-based association analysis using family data
| Â | Penetrance Set A | Penetrance Set B | Penetrance Set C | |||
|---|---|---|---|---|---|---|
Risk Haplotype # | SL-TDT | F_HapMiner | SL-TDT | F_HapMiner | SL-TDT | F_HapMiner |
2 | 0.06 | 0.12 | 0.36 | 0.58 | 0.17 | 0.30 |
3 | 0.08 | 0.07 | 0.54 | 0.73 | 0.27 | 0.42 |
4 | 0.09 | 0.13 | 0.65 | 0.90 | 0.41 | 0.68 |
5 | 0.11 | 0.17 | 0.60 | 0.92 | 0.63 | 0.88 |
6 | 0.10 | 0.30 | 0.90 | 0.97 | 0.55 | 0.73 |