Figure 1From: An integrative modular approach to systematically predict gene-phenotype associationsA flow chart of our approach pipeline for each phenotype. We designed a multiple objective simulated annealing (MOSA) algorithm to identify phenotype-specific coexpression modules in microarray datasets. We incorporated additional data sources into a random forest classifier to make novel gene-phenotype predictions. These modules and predictions were used to study human pleiotropy and phenotype-specific transcription regulation.Back to article page