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Figure 1 | BMC Bioinformatics

Figure 1

From: Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins

Figure 1

The process of analyzing a protein interaction network by the network-conversion approach. (a) A weighted interaction network is converted into (b) a hierarchical tree structure of proteins based on the path strength model and the functional similarity measurement. The edge weight was described as its thickness in (a). From the generated tree structure, (c) hub confidence is estimated for each node. From the selected structural hubs, (d) clusters as functional modules are identified.

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