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Figure 4 | BMC Bioinformatics

Figure 4

From: Discovering gene functional relationships using FAUN (Feature Annotation Using Nonnegative matrix factorization)

Figure 4

FAUN workflow. All genes in the gene list are used to construct a gene document collection from which a term-by-gene document matrix is constructed using GTP [46]. The matrix is then factored using rank k to produce a k-feature-NMF model. The resulting W and H matrix factors are used to extract dominant/significant terms and dominant genes for all k features. Dominant genes are then correlated for each feature. The FAUN user can annotate any feature and the resulting annotated NMF model can be used by the FAUN classifier to classify new gene documents.

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