Figure 2

Characteristics of Aβ aggregation as a function of initial monomer concentration. Concentration dependence of Aβ aggregation monitored by ThT fluorescence. A) Aggregation in five different initial concentrations of Aβ buffered in 20 mM Tris, 150 mM NaCl, pH 8.0, at 37°C. The data were fit using eq 1. B) Relation between the calculated lag-times and initial Aβ concentration and C) relation between rate of elongation and initial Aβ concentration.