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Table 2 Comparison of GOModeler results for the test cytokine dataset with manual analysis results. Columns with the heading G were generated by GOModeler and those with the heading of M were obtained by manual annotation by an immunologist.

From: GOModeler- A tool for hypothesis-testing of functional genomics datasets

Genes Hypothesis Terms
  TH2 Antigen Presentation Chemotaxis Metastasis Angiogenesis T Cell Activation Cell Proliferation Apoptosis
  G M G M G M G M G M G M G M G M
IL-2 1/-1    0 1   1   1/-1   1/-1 1 1 1 1/-1 -1
IL-4 1/-1 1   1 1 1    1/-1     1 1 -1 0
IL-6 1    0 1 -1 1 0 1   1   1/-1 0 -1/1  
IL-8      1 1 1 1 1 1    -1 -1 1  
IL-10 1 1   1 1   1 0    -1   -1 -1 -1/1 -1
IL-13   1            1 0   
IL-18 1 1       1 1 1 1   1 1 1 1
IFNg   -1 -1 1 1   1     1   1/-1 -1 1 1
TGFb   1    1   1   1/-1     -1 1 1/-1 -1
Effect
Sum of Pro 5 5 0 3 7 2 6 2 6 2 4 1 6 4 7 2
SumofAnti 0 -1 -1 0 0 -1 0 0 0 0 -1 0 -3 -3 -1 -3
Net 5 4 -1 3 7 1 6 2 6 2 3 1 3 1 6 -1