Identification of diagnostic subnetwork markers for cancer in human protein-protein interaction network

BMC Bioinformatics

Table 1 Statistics of the subnetwork markers identified by the proposed method.

θ			Size	Number of genes	Number of genes in common
		mean	standard deviation
1	USA	16.8	10.17	840	213
	Netherlands	14.62	8.69	731
2	USA	18.22	12.3	911	233
	Netherlands	16	10.34	801
4	USA	18	12.8	901	202
	Netherlands	17.28	11.4	864
8	USA	20.7	13.38	1035	252
	Netherlands	19.52	12.57	976
16	USA	20.2	11.13	1010	201
	Netherlands	16.64	10.89	832
∞	USA	22.32	14.86	1116	266
	Netherlands	21.92	10.67	1096

For each θ, we show the mean and standard deviation of the subnetwork size as well as the total number of genes covered by the identified subnetworks. We also show the number of genes shared by the subnetworks identified using the respective breast cancer datasets.

ISSN: 1471-2105