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Table 2 Enrichment analysis results for the sample subnetworks shown in Figure 1.

From: Identification of diagnostic subnetwork markers for cancer in human protein-protein interaction network

Subnetwork Attribute ID P-value Attribute name
A GO:0045165 0.024 cell fate commitment
  GO:0012501 0.001 programmed cell death
  GO:0008219 0.006 cell death
  GO:0016265 0.006 Death
  GO:0006915 0.017 Apoptosis
B GO:0000718 < 0.001 nucleotide-excision repair, DNA damage removal
  GO:0006308 0.046 DNA catabolic process
  GO:0043566 0.040 structure-specific DNA binding
C GO:0051318 0.039 G1 phase
  GO:0022403 < 0.001 cell cycle phase
  GO:0005654 < 0.001 Nucleoplasm
  GO:0000280 0.009 nuclear division
  GO:0007067 0.009 Mitosis
  GO:0048285 0.009 organelle fission
  GO:0051301 0.001 cell division
  GO:0022402 < 0.001 cell cycle process
  GO:0007049 0.000 cell cycle
  GO:0051726 0.008 regulation of cell cycle
  GO:0044428 0.001 nuclear part
  GO:0005634 0.024 Nucleus
D GO:0005838 < 0.001 proteasome regulatory particle
  GO:0000076 0.016 DNA replication checkpoint
  GO:0032297 0.016 negative regulation of DNA replication initiation
  GO:0030174 0.030 regulation of DNA replication initiation
  GO:0000502 0.010 proteasome complex
  GO:0031145 < 0.001 anaphase-promoting complex-dependent proteasomal ubiquitin-dependentprotein catabolic process
  GO:0051436 < 0.001 negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
  GO:0051352 < 0.001 negative regulation of ligase activity
  GO:0051437 < 0.001 positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
  GO:0051444 < 0.001 negative regulation of ubiquitin-protein ligase activity
  GO:0051443 0.001 positive regulation of ubiquitin-protein ligase activity
  GO:0051439 0.001 regulation of ubiquitin-protein ligase activity during mitotic cell cycle
  GO:0051351 0.001 positive regulation of ligase activity
  GO:0051438 0.002 regulation of ubiquitin-protein ligase activity
  GO:0051340 0.002 regulation of ligase activity
  GO:0010498 0.007 proteasomal protein catabolic process
  GO:0043161 0.007 proteasomal ubiquitin-dependent protein catabolic process
  GO:0022402 < 0.001 cell cycle process
  GO:0006511 0.050 ubiquitin-dependent protein catabolic process
  GO:0006259 0.050 DNA metabolic process
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BMC Bioinformatics

ISSN: 1471-2105

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