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Table 2 Enrichment analysis results for the sample subnetworks shown in Figure 1.

From: Identification of diagnostic subnetwork markers for cancer in human protein-protein interaction network

Subnetwork

Attribute ID

P-value

Attribute name

A

GO:0045165

0.024

cell fate commitment

 

GO:0012501

0.001

programmed cell death

 

GO:0008219

0.006

cell death

 

GO:0016265

0.006

Death

 

GO:0006915

0.017

Apoptosis

B

GO:0000718

< 0.001

nucleotide-excision repair, DNA damage removal

 

GO:0006308

0.046

DNA catabolic process

 

GO:0043566

0.040

structure-specific DNA binding

C

GO:0051318

0.039

G1 phase

 

GO:0022403

< 0.001

cell cycle phase

 

GO:0005654

< 0.001

Nucleoplasm

 

GO:0000280

0.009

nuclear division

 

GO:0007067

0.009

Mitosis

 

GO:0048285

0.009

organelle fission

 

GO:0051301

0.001

cell division

 

GO:0022402

< 0.001

cell cycle process

 

GO:0007049

0.000

cell cycle

 

GO:0051726

0.008

regulation of cell cycle

 

GO:0044428

0.001

nuclear part

 

GO:0005634

0.024

Nucleus

D

GO:0005838

< 0.001

proteasome regulatory particle

 

GO:0000076

0.016

DNA replication checkpoint

 

GO:0032297

0.016

negative regulation of DNA replication initiation

 

GO:0030174

0.030

regulation of DNA replication initiation

 

GO:0000502

0.010

proteasome complex

 

GO:0031145

< 0.001

anaphase-promoting complex-dependent proteasomal ubiquitin-dependentprotein catabolic process

 

GO:0051436

< 0.001

negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle

 

GO:0051352

< 0.001

negative regulation of ligase activity

 

GO:0051437

< 0.001

positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle

 

GO:0051444

< 0.001

negative regulation of ubiquitin-protein ligase activity

 

GO:0051443

0.001

positive regulation of ubiquitin-protein ligase activity

 

GO:0051439

0.001

regulation of ubiquitin-protein ligase activity during mitotic cell cycle

 

GO:0051351

0.001

positive regulation of ligase activity

 

GO:0051438

0.002

regulation of ubiquitin-protein ligase activity

 

GO:0051340

0.002

regulation of ligase activity

 

GO:0010498

0.007

proteasomal protein catabolic process

 

GO:0043161

0.007

proteasomal ubiquitin-dependent protein catabolic process

 

GO:0022402

< 0.001

cell cycle process

 

GO:0006511

0.050

ubiquitin-dependent protein catabolic process

 

GO:0006259

0.050

DNA metabolic process