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Table 2 Top ten functions/diseases and their respective top ten pathways in cp BVDV- infected monocytes

From: Analysis of Bovine Viral Diarrhea Viruses-infected monocytes: identification of cytopathic and non-cytopathic biotype differences

  Acute phase response signaling(12) Fcy receptor mediated phagocytosis in macrophages and monocytes (8) Actin cytoskeleton signaling (8) Antigen presentation pathway (3) B cell development (3) RhoA signaling(5) Caveolae- mediated endocytosis signaling (4) Clathrin- mediated endocytosis signaling (6) IL-10 signaling(3) Interferon signaling(2)
Cellular function and maintenance (7) FGR, LYN ITGB3 ITGB3
cell-to-cell signaling and interaction (8) F2 FGR, LYN CD14, F2 ITGB3 F2, ITGB3 CD14
Inflammatory response (14) F2 FGR, LYN CD14, F2 TAPBP HLA-DQB1 ITGB3 F2, ITGB3 CD14
Cellular assembly and organization (2) FGR, LYN
Protein synthesis (2) FGR, LYN
Cellular compromise (6) FGR, LYN ITGB3 ITGB3
Cell morphology (3) FGR, LYN
Cellular development (4) FGR, LYN ITGB3 ITGB3
Hematological system development and function (9) F2 FGR, LYN CD14, F2 SPN ITGB3 F2, ITGB3 CD14
Immune cell trafficking (9) F2 FGR, LYN F2 SPN ITGB3 F2, ITGB3
  1. F2: Coagulation Factor II (thrombin); FGR: Fibrinogen Gamma Chain; LYN: v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; TAPBP: TAP Binding protein (Tapasin); SPN: Sialophorin; ITGB3: Integrin, Beta 3 (platelet glycoprotein IIIa, antigen CD61) Numbers between brackets indicates the number of altered proteins involved in the functions/diseases or pathway