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Table 3 Differentially altered proteins represented in top ten immunological pathways when comparing cp to ncp BVDV infection

From: Analysis of Bovine Viral Diarrhea Viruses-infected monocytes: identification of cytopathic and non-cytopathic biotype differences

   Regulation  
Symbol Entrez Gene Name Cp Ncp Pathways
HMOX1 heme oxygenase (decycling) 1 Up Up Acute Phase Response Signaling, Fcy Receptor-mediated Phagocytosis in
     Macrophages and Monocytes, IL-10 Signaling
ALB albumin Down Down Acute Phase Response Signaling, Caveolar-mediated Endocytosis Signaling
HP haptoglobin Down Down Acute Phase Response Signaling
SOD2 superoxide dismutase 2, mitochondrial Up Up Acute Phase Response Signaling
TF transferrin Up Up Acute Phase Response Signaling, Clathrin-mediated Endocytosis Signaling
APOH apolipoprotein H (beta-2-glycoprotein I) Up Acute Phase Response Signaling
APOA1 apolipoprotein A-I Up Acute Phase Response Signaling
AHSG alpha-2-HS-glycoprotein Up Up Acute Phase Response Signaling
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 Up Up Acute Phase Response Signaling
  antiproteinase, antitrypsin), member 1    
A2M alpha-2-macroglobulin Up Up Acute Phase Response Signaling
FGG fibrinogen gamma chain Up Acute Phase Response Signaling
F2 coagulation factor II (thrombin) Up   Acute Phase Response Signaling, Actin Cytoskeleton Signaling, Clathrin-
     mediated Endocytosis Signaling
ACTR3 ARP3 actin-related protein 3 homolog (yeast) Up Up Fcy Receptor-mediated Phagocytosis in Macrophages and Monocytes, Actin
     Cytoskeleton Signaling, RhoA Signaling, Clathrin-mediated Endocytosis
     Signaling
ARPC2 actin related protein 2/3 complex, subunit 2, Up   Fcy Receptor-mediated Phagocytosis in Macrophages and Monocytes, Actin
  34kDa    Cytoskeleton Signaling, RhoA Signaling, Clathrin-mediated Endocytosis
     Signaling
EZR ezrin Down   Fcy Receptor-mediated Phagocytosis in Macrophages and Monocytes, Actin
     Cytoskeleton Signaling, RhoA Signaling
LYN v-yes-1 Yamaguchi sarcoma viral related Up   Fcy Receptor-mediated Phagocytosis in Macrophages and Monocytes
  oncogene homolog    
TLN1 talin 1 Down Fcy Receptor-mediated Phagocytosis in Macrophages and Monocytes
FYB FYN binding protein (FYB-120/130) Down Fcy Receptor-mediated Phagocytosis in Macrophages and Monocytes
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) Down Down Fcy Receptor-mediated Phagocytosis in Macrophages and Monocytes
  oncogene homolog    
MYH10 myosin, heavy chain 10, non-muscle Up Actin Cytoskeleton Signaling
MYL6 myosin, light chain 6, alkali, smooth muscle and Up   Actin Cytoskeleton Signaling, RhoA Signaling
  non-muscle    
DIAPH3 diaphanous homolog 3 (Drosophila) Down Actin Cytoskeleton Signaling
CD14 CD14 molecule Up Up Actin Cytoskeleton Signaling, IL-10 Signaling
IQGAP1 IQ motif containing GTPase activating protein 1 _ Up Actin Cytoskeleton Signaling
HLA-DRB1 major histocompatibility complex, class II, DR Up Up Antigen Presentation Pathway, B Cell Development
  beta 1    
TAP1 transporter 1, ATP-binding cassette, sub-family Down Down Antigen Presentation Pathway, Interferon Signaling
  B (MDR/TAP)    
TAPBP TAP binding protein (tapasin) Down Antigen Presentation Pathway
HLA-DQB1 major histocompatibility complex, class II, DQ Down   B Cell Development
  beta 1    
SPN sialophorin Down Down B Cell Development
PTPRC protein tyrosine phosphatase, receptor type, C _ Up B Cell Development
KTN1 kinectin 1 (kinesin receptor) Down Down RhoA Signaling
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of Up Down Caveolae-mediated Endocytosis Signaling
  IIb/IIIa complex, antigen CD41)    
FLNA filamin A, alpha Up Up Caveolae-mediated Endocytosis Signaling
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, Up Down Caveolae-mediated Endocytosis Signaling, Clathrin-mediated Endocytosis
  antigen CD61)    Signaling
ITGA6 integrin, alpha 6 Down Caveolae-mediated Endocytosis Signaling
SH3GLB1 SH3-domain GRB2-like endophilin B1 Down Clathrin-mediated Endocytosis Signaling
ARG2 arginase, type II Up Up IL-10 Signaling
MX1 myxovirus (influenza virus) resistance 1, Up   Interferon Signaling
  interferon-inducible protein p78 (mouse)