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Table 1 Centrality measurements for the RNA targets in the protein-protein interaction network

From: Modularity of Escherichia coli sRNA regulation revealed by sRNA-target and protein network analysis

  All Experimental Experimental and predicted
  mean mean Sim. mean p-val mean Sim. mean p-val
Deg 7.9 11 7.9 0.16 7.0 7.9 0.66
Bet 2.2e-03 4.2e-3 2.2e-3 0.098 2.2e-3 2.2e-3 0.44
Clo 0.28 0.3 0.28 0.022 0.27 0.28 0.59
CC 0.11 0.21 0.11 0.037 0.12 0.10 0.20
CPL 3.7 2.6 3.7 0.015 3.6 3.7 0.23
Den 6.5e-03 0.14 6.5e-3 0.019 0.063 6.2e-3 0.028
IDR N/A 6.5e-3 3.4e-4 9.0e-3 5.8e-3 5.0e-4 0.011
I/T   28/65 85/240
   Experimental & extended Exp & pred & both extended
Deg   Mean Sim. mean p-val Mean Sim. mean p-val
Deg   9.3 7.9 0.28 7.4 7.9 0.62
Bet   3.4e-3 2.2e-3 0.14 2.0e-3 2.2e-3 0.57
Clo   0.29 0.28 0.051 0.27 0.28 0.87
CC   0.19 0.11 0.027 0.14 0.10 0.017
CPL   3.0 3.7 0.020 3.4 3.7 5.0e-3
Den   0.085 7.0e-3 0.015 0.14 5.8e-3 0.0
In-d   4.0e-3 5.5e-4 0.032 9.5e-2 7.9e-4 0.0
I/T   38/92 144/450
  1. Those with significant values (p < 0.05) are indicated in boldface and those close to a p-value of 0.05 are underlined. The extended targets are targets located downstream of experimental or predicted sRNA targets in the same operon. Deg: Degree, Bet: Betweenness, Clo: Closeness, CC, Clustering coefficient, CPL: Characteristic path length Pat: Path length, Den: Density, IDR, In-degree ratio, I/T: sRNA in the network/total sRNA