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Table 1 The value and definition of system parameters

From: Sensitivity analysis of dynamic biological systems with time-delays

Parameter

Definition

Value

h 0

Uncontrolled heart rate

100 bpm

p 0

Mean arterial blood pressure

100 mm Hg

α

Sympathetic effect on peripheral resistance

15

β

Sympathetic control of heart rate

10

ν

Strength of vagal tone

9.63

δ

Relaxation time

0.8 s-1

γ

Damping effect of vagal activity on the sympathetic tone

0.2

μ

3/(2 + α)

0.18

A 1

Amplitude of the influence of respiration on blood pressure

0

A 2

Amplitude of the influence of respiration on heart rate

0.003

f r

Breathing rate

0.17 Hz

Ï„

Sympathetic time delay

3 s

Ï•

Phase lag

3.14 s

n

Hill exponent

8

ε h

Relative coefficient for heart rate

1

ε p

Relative coefficient for blood pressure

3

  1. The definition of system parameters in the DDE model developed by Ottesen [34]. The parameter values are obtained from the literature [35].