Figure 5

Choosing more than one anchor genomes can rescue missing ortholog groups. This cartoon figure illustrated examples of three different ortholog group distributions in four species A, B, C and D. Four rectangles in gray line stand for four different genomes. Protein sequences and domain are shown as line and rectangles. As shown in the figure, there are total three different ortholog groups in which group 1 exist in all genomes, group 2 is a clade 2 specific ortholog group and group 3 had a gene miss event in genome A. When choose species A in clade 1 as the anchor genome, DODO will only report group 1 and both group 2 and group 3 will be missed. Those missing ortholog groups could be identified if choose multiple genomes as anchor genomes in DODO pipeline.