Table 3 Co-occurrence of Pfam domains in IDD clusters
From: Intrinsically disordered domains deviate significantly from random sequences in mammalian proteins
Immune | Obs./Expect | Non-immune | Obs./Expect | Short Name | Full Name | Function (Uniref ID) |
|---|---|---|---|---|---|---|
1 (5/30) | 2.54 | 18 (3/11) | 3.12 | SH2 | SH2 domain | Signal transduction (P05480) |
3 (3/11) | 5.06 | 41 (2/20) | 2.75 | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) | RNA binding & signal transduction (P97433) |
6 (2/3) | 16.90 | 18 (5/21) | 2.72 | Guanylate_kin | Guanylate kinase | Possible Signal transduction (B9EHJ3 ) |
6 (2/25) | 2.03 | 18 (3/11) | 3.12 | bZIP_1 | bZIP transcription factor | Transcription (P01101) |
38 (3/25) | 6.35 | 31 (3/40) | 4.83 | SH3_1 | SH3 domain | Adaptor (Q64010) |
72 (2/15) | 5.00 | 55 (2/30) | 2.53 | 7tm_1 | 7 transmembrane receptor (rhodopsin family) | GPCR (O09047) |
100 (2/33) | 7.27 | 38 (6/48) | 2.88 | zf-C2H2 | Zinc finger, C2H2 type | Possible transcription regulator (Q8C687) |
100 (2/10) | 24.00 | 38 (3/10) | 6.90 | KRAB | KRAB box | Possible transcription regulator (Q8BIV1) |
115 (1/5) | 7.35 | 26 (2/6) | 2.94 | ARID | ARID/BRIGHT DNA binding domain | Possible transcription regulator (Q3U108) |
175 (2/12) | 12.50 | 2 (2/13) | 5.16 | fn3 | Fibronectin type III domain | Putative neuronal cell adhesion molecule (Q8BQC3) |