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Table 1 Deregulated human genes and their contributed Gene Ontology in a xenograft model.

From: Stromal microenvironment processes unveiled by biological component analysis of gene expression in xenograft tumor models

Gene Ontology Enrichment from the Differentially Expressed Genes

Expression of Significantly Differentially Expressed Probes in Human Array

Xhyb probes

Remainders

 

Biological process chiefly attributable to mouse stromal cells

ci,jMm » ci,jHs

ci,jHs is stochastically distributed

Biological process chiefly attributable to human cancer cells

ci,jMm is stochastically distributed

ci,jMm « ci,jHs

Biological processes enriched in the experiment

Both ci,jMm and ci,jHs are stochastically distributed

  1. This table describes the relationship between deregulated genes and their contributed Gene Ontology in a xenograft model, using human microarray. Legend: ci,jHs is the main effect of a clinical phenotype j on a Homo sapiens (Hs) gene targeted by a probeset i; where ci,jMm is the main effect of a clinical phenotype j on a Mus musculus (Mm) gene cross-hybridized by a probeset i.