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Table 1 Taxonomy of multi-item ADE associations

From: Mining multi-item drug adverse effect associations in spontaneous reporting systems

Drugs

1a

Drug-drug interactions found that are known

4%

1b

Drug-drug combinations known to be given together or treat same indication

78%

1c

Drug-drug combinations that seem to be due to confounding

9%

1d

Drug-drug interactions that are unknown

9%

Associations

2a

Associations (drug[s]-event) that are known

67%

2b

Associations (drug[s]-event) that are unknown

33%