Skip to main content

Table 4 High/not high model

From: An integrative method for scoring candidate genes from association studies: application to warfarin dosing

Gene

Name

P-Value

VKORC1

Vitamin K1 2,3-epoxide reductase subunit 1

4.39E-06

CYP2C9

cytochrome P450, family 2, subfamily C

2.27E-04

QTRTD1

queuine tRNA-ribosyltransferase domain

3.21E-04

NAT13

N-acetyltransferase 13

5.25E-03

BAT5

HLA-B associated transcript 5

6.76E-03

CRP

C-reactive protein, pentraxin-related

1.02E-02

COL1A2

Alpha-2 type I collagen

1.37E-02

GGCX

Vitamin K gamma glutamyl carboxylase

1.44E-02

A2M

C3 and PZP-like alpha-2-macroglobulin

2.06E-02

FBXO28

F-box protein 28

2.14E-02

HSD3B7

3-beta-HSD VII

2.54E-02

ITGA5

Fibronectin receptor subunit alpha

4.07E-02

ALS2

amyotrophic lateral sclerosis 2

4.13E-02

NSUN6

NOL1/NOP2/Sun domain family 6

4.21E-02

SORBS3

sorbin and SH3 domain containing 3

4.99E-02

  1. Top 15 genes with candidate gene-scores that significantly distinguish between high dose patients and non-high-dose patients (p≤0.05). P-Values are result of t test between low-dose and non-low-dose distributions of gene-scores. Genes in bold are significant after correcting for multiple hypothesis testing.