Table 1 Reactions modeling transcription
From: Stochastic sequence-level model of coupled transcription and translation in prokaryotes
Event | Reaction | Rate constant | Ref. |
|---|---|---|---|
Initiation and promoter complex formation (1) |
| k init = 0.015 τ oc = 40 ± 4 | [21] |
Promoter clearance (2) |
| k m = 114 | [37] |
Elongation (3) |
| k m = 114 | [37] |
Activation (4) |
| k a = 114, n>10, k a = 30, n≤10 | [37] |
Pausing (5) |
| k p = 0.55 τ p = 3 | [2] |
Pause release due to collision (6) |
| k m = 114 | [38] |
Pause induced by collision (7) |
| k m = 114 | [38] |
Arrests (8) |
| k ar = 0.00028 τ ar = 100 | [5] |
Editing (9) |
| k ec = 0.008 τ c = 5 | [2] |
Premature termination (10) |
| k pre = 0.00019 | [39] |
Pyrophosphorolysis (11) |
| k pyro = 0.75 | [40] |
Completion (12) |
| k f = 2 | [41] |
mRNA degradation (13) |
| k dr = 0.011 | [13] |
