BMC Bioinformatics

Table 6 Rules inferred by GRNCOP2

From: Discovering time-lagged rules from microarray data using gene profile classifiers

						Rule found by
Rules						GRNCOP	Soinov et. al.	Bulashevska and Eils
+/-	CLB1	0	→	+/-	CLB2	*	-	+
+/-	CLB1	3	→	+/-	CLB5
+/-	CLB1	3	→	+/-	CLB6
+/-	CLB1	0	→	-/+	CLN2	*
+/-	CLB1	0	→	+/-	SWI5	*
+/-	CLB2	0	→	+/-	CDC20
+/-	CLB2	0	→	+/-	CLB1	*	*	+
+/-	CLB2	3	→	+/-	CLB5
+/-	CLB2	3	→	+/-	CLB6
+/-	CLB2	0	→	-/+	CLN2
+/-	CLB2	0	→	+/-	SWI5	*
+/-	CLB5	4	→	+/-	CLB2
+/-	CLB5	0	→	+/-	CLB6	*	+
+/-	CLB5	3	→	-/+	CLB6
+/-	CLB6	0	→	-/+	CLB1			+
+/-	CLB6	0	→	+/-	CLB5	*	+
+/-	CLB6	3	→	-/+	CLB5
+/-	CLB6	0	→	+/-	CLN2	*
+/-	CLB6	1	→	+/-	CLN2
+/-	CLN1	0	→	+/-	CLB6	*
+/-	CLN1	2	→	-/+	CLB6
+/-	CLN1	0	→	+/-	CLN2	*
+/-	CLN2	4	→	+/-	CLB2
+/-	CLN2	0	→	+/-	CLB5	*
+/-	CLN2	0	→	+/-	CLB6	*
+/-	CLN2	2	→	-/+	CLB6
+/-	CLN2	3	→	-/+	CLB6
+/-	SIC1	0	→	+/-	CLB5
+/-	SWI4	0	→	+/-	CLB5
+/-	SWI4	4	→	-/+	CLB5
+/-	SWI5	0	→	+/-	CDC20	*
+/-	SWI5	0	→	+/-	CLB2	*		+
+/-	SWI5	3	→	+/-	CLB6

Rules inferred by GRNCOP2 using 20 cyclin genes of the datasets from Spellman et al. (1998). The last three columns indicate whether the rules were found by any of the other methods. The complete rules are represented by an *; + for positive regulatory relationship, and - for the negative regulatory relationship.

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