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Table 2 NCI/Nature pathways with highest differential behavior in GBM tumor samples.

From: The PathOlogist: an automated tool for pathway-centric analysis

Top 15 NCI/Nature Pathways - Activity p-value
signaling events mediated by hdac class i(nci/nature) 8.56E-05
cellular roles of anthrax toxin(nci/nature) 8.70E-05
hiv-1 nef: negative effector of fas and tnf-alpha(nci/nature) 8.70E-05
nephrin/neph1 signaling in the kidney podocyte(nci/nature) 8.84E-05
class ib pi3k non-lipid kinase events(nci/nature) 8.98E-05
p38 signaling mediated by mapkap kinases(nci/nature) 9.42E-05
hypoxic and oxygen homeostasis regulation of hif-1-alpha(nci/nature) 1.09E-04
hif-1-alpha transcription factor network(nci/nature) 1.16E-04
amb2 integrin signaling(nci/nature) 1.18E-04
signaling events mediated by prl(nci/nature) 1.36E-04
vegfr1 specific signals(nci/nature) 1.36E-04
caspase cascade in apoptosis(nci/nature) 1.39E-04
s1p3 pathway(nci/nature) 1.83E-04
bard1 signaling events(nci/nature) 2.02E-04
lpa receptor mediated events(nci/nature) 2.22E-04
Top 15 NCI/Nature Pathways - Consistency p-value
nephrin/neph1 signaling in the kidney podocyte(nci/nature) 8.56E-05
hiv-1 nef: negative effector of fas and tnf-alpha(nci/nature) 8.56E-05
rac1 signaling pathway(nci/nature) 8.56E-05
class ib pi3k non-lipid kinase events(nci/nature) 8.98E-05
cdc42 signaling events(nci/nature) 9.73E-05
bard1 signaling events(nci/nature) 1.05E-04
hypoxic and oxygen homeostasis regulation of hif-1-alpha(nci/nature) 1.12E-04
signaling events mediated by focal adhesion kinase(nci/nature) 1.14E-04
regulation of p38-alpha and p38-beta(nci/nature) 1.40E-04
alpha-synuclein signaling(nci/nature) 1.83E-04
signaling events mediated by hdac class i(nci/nature) 1.97E-04
pdgfr-beta signaling pathway(nci/nature) 2.04E-04
fas (cd95) signaling pathway(nci/nature) 2.39E-04
igf1 pathway(nci/nature) 2.77E-04
noncanonical wnt signaling pathway(nci/nature) 3.09E-04