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Table 3 Summary of the five available 3D structures of the lactose permease

From: Hydrophobic pulses predict transmembrane helix irregularities and channel transmembrane units

PDB file

C154G mutant

Specificity

Resolution

1PV6

Yes

Native

3.5

1PV7

Yes

With bound substrate homolog

3.6

2V8N

No

Native

3.6

2CFP

Yes

Acidic pH (5.6)

3.3

2CFQ

Yes

Neutral pH (6.5)

2.95

  1. The C154G lactose permease mutant, which binds to ligands but catalyzes little transport, is used to obtain well-diffracting crystals.