Hydrophobic pulses predict transmembrane helix irregularities and channel transmembrane units

BMC Bioinformatics

Table 4 Sub-helix extremities of lactose permease

2CFP	2CFQ	2V8N	1PV6	1PV7	G1-HPulses
-	-	-	2	2	-
8	7	7	7	7	7
30	29	-	-	-	27
42	45	45	42	42	43
59	63	60	-	-	61
-	75	75	74	74	74
87	86	-	-	-	82
-	95	94	-	-	89
104	104	104	104	104	101
120	115	121	120	120	122
143	-	-	140	140	136
-	149	147	-	-	153
-	166	166	166	166	166
177	179	-	-	-	174
-	-	-	-	-	191
210	210	210	210	210	205
220	220	220	220	220	220
235	-	232	-	-	-
244	-	243	-	-	242
257	257	254	254	254	257
269	-	265	-	-	268
288	288	288	288	288	290
312	312	312	312	312	310
325	-	325	-	-	323
-	343	346	346	346	341
357	-	358	357	357	359
377	378	378	378	378	374
-	-	-	-	-	393
-	-	-	408	408	404

For each TMH of each 3D model, we reported the start (amino acid position) of the sub-helices. G1-HPulse predictions are also reported. Positions found in all are bolded. Positions of G1-HPulses that were not found in any model are indicated in italic.

ISSN: 1471-2105