Figure 2
From: Predicting disease-associated substitution of a single amino acid by analyzing residue interactions
Importance score of each feature determined by using the random forest algorithm in the R package. Scores were averaged over 100 times. Here, suffices W, M and N indicate wild-type, mutant and environment, respectively. For environmental features, suffix numbers were used to indicate different neighboring residues. det_Frequency denotes the frequency difference between wild-type and mutant residues whereas det_PSSM denotes the PSSM score difference between wild-type and mutant residues.