From: Predicting disease-associated substitution of a single amino acid by analyzing residue interactions
Methods | Sensitivity (%) | Specificity (%) | ACC (%) | MCC |
---|---|---|---|---|
All feature set | 86.6 | 71.9 | 80.8 | 0.59 |
37-feature set | 87.3 | 72.1 | 81.3 | 0.60 |
SIFT | 79.5 | 71.3 | 76.3 | 0.51 |
PolyPhen-2 | 74.1 | 78.1 | 75.7 | 0.51 |
Bongo | 21.6 | 84.7 | 46.6 | 0.09 |