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Figure 3 | BMC Bioinformatics

Figure 3

From: A hidden two-locus disease association pattern in genome-wide association studies

Figure 3

Distributions of genotypes of rs668860 and rs10873672 in the bipolar disorder data set and the odds ratio computed for combined genotypes of these two SNPs. Left Panel: The distribution of genotypes of rs668860 and rs10873672 in case samples. Middle Panel: The distribution of genotypes of rs668860 and rs10873672 in control samples. Right panel: The estimated odds ratio for the combination of rs668860 and rs10873672. The odds ratio of genotype combination "AA/TT" is used as reference. The genotype combination "TT/CT" has significantly higher odds ratio than other genotype combinations.

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